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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Ancienne marionnette indienne tête en bois sculptéBOGLINS BLAP 1987 HAND PUPPET RARE MATTEL EXCELLENT CONDITION WITH BOXEnsemble De Marionnettes À Main red Et Doigt Marionnette  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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Old Wind Up Dog Toy

By Connor Emdin
September 26, 2018

Living Puppets Handpuppe Peterchen 45 cm NeuLiving Puppets® Handpuppe Peer der Pirat 65 cm W033Marionnette Caricature Satirique Ancienne Antique Puppet Satirical ToysPelham Hand Made & Hand Painted Puppet Hansel 1960's Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.VINTAGE 1950s ARNOLD HELIBUS TIN LITHO WIND HELECOPTER PARTS OR RESTORATION Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Bros Warren Couch 1994 Figure Statue Bunny Bugs Potatoe 3cf40iwyo61785-Toys & Games

Item specifics

Condition:
Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
Year: 1994
Type: Figure
Warren Bros 1994 Couch Potatoe Bugs Bunny Statue Figure

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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BUKI PM854 - Marbles Run

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By Lea Borgi, MD
May 16, 2018

SENTINEL RIOBOT BLODIA-RIOT BX-07R MARVEL VS CAPCOM DIECAST FIGURE ESPOSTOTakatoku Fuji Zero family bouken famiri hibari no popy popinicaVINTAGE 80'S SPACE MOVER Battery Operated Vehicle DEFENDER for Star Wars G.I Joe Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”