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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Ducomi® Lux & Co. – Luxury Designer Combination Scarf and Hat in Soft Wool withAurora World 09978 Winter Bonnie Bear 13InStar Wars Yoda 8 Plush Soft Toy  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

Unique 18 Inches Cute Plush Alpaca Toy Llama Stuffed Animal for Kid Hat and TieCorduroy Bear 13 Soft Toy Corduroy 13 Keel Toys BERTIE Sitting TEDDY BEAR 45cm Large Soft Toy BROWNPMS 16 E.T LARGE GIFT PLUSH CLASSIC Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Waffles Brown Bear Stuffed Animal 11 High Sitting Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

100cm Long LARGE HUGE BROWN MONKEY SOFT TOY Teddy PLUSH Kids Boys Girls Toy GiftNEW Jellycat Lollopylou Unicorn Comforter Soother Baby Ribbons Soft Toy BNWTAdult Men's History Tudor Medieval King Henry VIII Fancy Dress Costume StandardMelissa Doug 18520 Examine and Treat Pet Vet Play Set (24 pcs) Role, Multi Col 110cm Giant Large Big Chameleon Lizard Stuffed Animal Plush Toy Doll Pillow Gift

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CAMPIONISSIMI SUPER GOAL GIG COMPLETO

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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By Lea Borgi, MD
May 16, 2018

Gund Gudetama “Two Lazy Eggs and Sausage” Plush, 8.5 Inches Toy, YellowAqua the Sloth 16 bluee Squishmallows by Kellytoy Plush Animal Pillow NEW NWTNEW (Set) Perfect Petzzz Breathing Beagle Dog And Mini Beagle - Plush Synthetics Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”