Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

Peluche Trudi 23967 - Coccinella Sofia Peluche 20cm

By Olivier Lucar
October 16, 2018

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Burton & Burton Wall Hanging Bunny Hind End

By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

BABY STARTERS BROWN MONKEY blueE POLKA DOT RATTLE SECURITY BLANKET STUFFED PLUSHGanz Cottage Collectibles Darby and Choo choo railroad Trains pair nursery EUCOrso Polare Placido Sdraiato piccolo 25122 Trudi 24cm PelucheRilakkuma stuffed animal large 70cm with hidden component Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery”

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.TALKING PADDINGTON BEAR From The MOVIE Soft Cuddly Toy Talks NEW FREE P&P Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

Old tiger soft toy about 50 year old

By Martina McGrath, MD
July 18, 2018

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Item specifics

Status: Retired Theme: Cats
Brand: Jellycat Type: Soft Toys
Character Family: Junglie bunglie Size: Small (15-35 cm)

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Marvel Thor 10 Soft Toy

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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Intelex, Warmies Cozy Therapy Plush - Bunny

By Lea Borgi, MD
May 16, 2018

Kellytoy Squishmallow 16 Simon The Sloth Super Soft Plush Toy Pillow Pet PalGUND Peter Rabbit GOSH Peter Rabbit Doctors Bag Soft ToyJellycat Small Berry Bashful Bunny BNWT Rabbit Soft Toy Suitable from Birth Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”