Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

AQUA STUFFED NATURE SHOEBILL S 00130169VidaXL Dog Cuddly Toy Plush Brown 120 cm P1Z4Trudi Tati Sitting Husky Dog 14 inches  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

Teddy Bear Walker 2.4 Walking Dead x Funko Mystery Minis Vinyl Mini-Figure

By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

Big Plush Animal Penguin Toy Stuffed Cartoon Penguins Doll 40cm Kid Cushion GiftBath Body Works Cream Softest Lambie Lamb Sheep Plush Stuffed BIG 18'' NEW 2018Lemonwood Asia White Plush Red Hearts Heart Nose Furry Fuzzy Kitty Puppy 8

Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

Warmies - Giraffa Peluche Termico

By Olivier Lucar
October 16, 2018

Mary Meyer Sugar and Spice Teddy Bear Plush Stuffed Animal Toy Tan 56680 7 Space Red Angry Birds Plush Oversized 18 Stuffed Animal Toy with SoundPlush Stuffed Pug [ID 8605]Large DanDee Plush CHOCOLATE BUNNY Stuffed Brown Rabbit Collectors Choice EASTERFunko POP Plush - Marvel - SPIDER-GWEN (Jumbo Size - 16 inch) - New Stuffed ToyNEW LUFSIG Soft toy, wolf

Rare MIKE DOG Plush Stuffed Animal Toy 17 - 24 inch monkey swinging

By Connor Emdin
September 26, 2018

Simba Lalka Steffi na skuterzeHansa Meerkat Plush Toy (33cm) BRAND NEWLarge Squishmallow Jaime The Rainbow Unicorn Kellytoy NWT Squishmallows New Hanna Barbera Cartoon Ranger Smith Wally Gator Plush Toy Factory Doll Lot Set Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

AMUSE Plush Wooly 15 Long - Fuwamoko Series Plush - WhiteDragon Age Inquisition Dorian Plush Doll ONLY + Collectors Card 10 TALL BiowarePuton Pig Plush Pink 9.8 (25cm) M Size - F S Japan Stuffed Animal Fluffy ToyBoyds Bears purple C. Bloomin' Beary 10 Plush Bear NWT- 2010 Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery”

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Ty Beanie Boos - Ice Cube the Penguin 15cm Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

Squeezamals Dan The Dog, a Large Slow Rise, Cuddly, Soft, Squshie, Sweet Scen...

By Martina McGrath, MD
July 18, 2018

Elf on the Shelf Girl Plush w Multiple Different Outfits Christmas Dressup DollRARE REALISTIC LIFELIKE PLUSH DOLL FIGURE DOUGLAS PET WRINKLED PUG PUPPY DOG TOYLot of 4 Rope Or Yarn 1 Stuffed Floppy Ear Bunny Rabbit Dolls MTY InternationalJumbo 34 Easter Lamb Sheep Plush Cream color stuffed animal toy Altec Lansing MZX662 High Performance Over-Ear Headphones with In-Line Mic - Red



Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Wilberry - Mini - 15cm Pug Soft Toy

By Connor Emdin
June 27, 2018

Nici 38618, Hippo Balduin, 15 cm, Soft ToyCuddle Toys 4452 Kyle German Shepherd Handful ToyCuddle Toys 2037 41 cm Long Wolfgang Pointer Plush ToySigikid Sigikid38709 Patchwork Sweety Elephant, 31 x 17 x 15 cm, Multi-color Jellycat - Bashful Bunny - Cream - Small

Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

Aurora World 12-inch Yummy Bear (Pink)

By Martina McGrath, MD
June 5, 2018

Esotec 102089 Solar Path Marker Lights Set of 2 Light Colour Warm White 3000 K 7Aurora World 60830 BBC The Gruffalo Baby Plush Rattle Aurora World 60772 8-Inch Crikee Crocodile Soft Toy

The Puppet Company - Full Bodied Animals - Border Collie Dog Puppet

Hallmark Cuddly Comfort Heartbeat Teddy Bear Stuffed Animal

By Lea Borgi, MD
May 16, 2018

Wildlife Artists Baby Orangutan Plush Toys 10 Stuffed Baby Orangutan, KidsTrudi Puppet (25 cm, Mouse)BETOYS 934740468 – Hopscotch Foam Mat 10 Tiles Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”