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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

15 VINTAGE GUND TENDERHEART WHITE TEDDY BEAR RED HEART STUFFED ANIMAL PLUSH TOYHorse Pony Plush Teddy Bear Breyer Animal Creations Stuffed Animal 2007 Toy DollPOKEMON SOLE LUNA ARCANINE ALOLA 30 CM PELUCHE Growlithe Arcanin 59 Arkani acquaTrudi Brown Plush Ettore Teddy Bear 35cm 14in Seam and Hang Tags Cuddly16 VINTAGE 1985 WORLD WILDLIFE FUND ORANGUTAN MONKEY STUFFED ANIMAL PLUSH TOYLittle Buddy Kirby Adventure All Star Collection 5 Waddle Dee Stuffed Plush

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By Connor Emdin
September 26, 2018

Miss oh Stuffed Plush Soft Toy Stofftier realistic Bubo Owl 1532cm10 Animal Adventure Target Purple & Pink Plush Kitty Cat 2012Jake & Amos Bear Plush 1990 Sits 11 Vintage Bell Oil Company Plush Bell Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Squeezamals BH31712.4300 a Large Slow Rise, Cuddly, Soft, Squshie, Sweet Scen... Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Vintage Bear Smarty Talking Toys Galoob Lewis 1985 3cf40dgaq12306-Toys & Games

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Vintage 1985 Lewis Galoob Toys Talking Smarty Bear

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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By Lea Borgi, MD
May 16, 2018

Warmies, Intelex Cozy Plush Bear, BrownBIG LIFELIKE DOUGLAS SCOTTISH TERRIER PUPPY DOG REALISTIC PLUSH STUFFED ANIMALCuddle Toys 3780 Simon Sloth Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”