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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Warhammer 40K 5th Limited Edition Core Rulebook w Ammo BoxWest End Star Wars Wretched Hives of Scum & Villainy SC EXChaosium Superworld Worlds of Wonder Box VG+  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

TSR Basic D&D Quagmire SC VG+

By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset


Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

UltraPro 84695 Gravity Dice Set 2 D6 Factory Sealed

By Olivier Lucar
October 16, 2018

FFG Star Wars Imperial Assault Regional Dice 2019 Complete SetStar Wars Bladebuilders Bundle Spin action RRP 59.99 XMAS ChristmasStar wars legion Endor Rebel Strike team,Troopers Painted 7 miniaturesStar Wars Miniatures Ultimate Missions Rebel Storm New and Shrink wrappedStar Wars X-Wing Scum And Villainy Conversion Kit NEW & SEALEDVampire the Masquerade RPG 5th edition PRESALE Camarilla supplement modiphius N


By Connor Emdin
September 26, 2018

Star Wars X-Wing case for 2 Shuttles, Slave 1, 14 fighters on stands (E-227)10mm ACW confederate - american civil war command - command (17920)10mm Roman era roman - cataphracts 12 figs - inf (22420)10mm WW2 russian - battle group (as photo) - inf (33814) Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

15mm 7YW hungarian - regiment 32 figures - inf (27352)15mm ACW confederate - regt. 21 figures - inf (25759)15mm ACW union - regt. 24 figures - inf (26893)15mm classical persian - battle group 20 figures - cav (26928) Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery”

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Bloodlines The Hidden, City of the Damned New Orleans, and Storytellers Screen Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

Evil Hat Horror RPG Don't Rest Your Head SC VG+

By Martina McGrath, MD
July 18, 2018

15mm dark ages turkish - battle group 13 figures - cav (33598)15mm medieval mongol - heavy 15 figures - cav (27391)15mm napoleonic french - line 24 figures - inf (31393)15mm napoleonic saxon infantry division 6 battalions Kingdom Death Female Survivor Resin Kit - Boxed + Art Card

Quad Masterscreen RPG d20 Zip Citizen NM 3cf40azct21060-Toys & Games

Item specifics

Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
Brand: Citizen Games
MPN: CIT2100 UPC: Does not apply
Citizen d20 RPG Masterscreen Quad Zip NM

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Shadows in the Dark Mekhet - Vampire The Requiem - VGC

By Connor Emdin
June 27, 2018

15mm scifi lizard - combat team 10 figures - inf (23828)15mm WW2 british - section (as photo) - inf (32264)18mm 12 x Pro Painted AB French Napoleonic Hussars20mm modern american - section 12 figures - inf (35817) Trail of Cthulhu RPG - Core Rules + Bonus Book (Gumshoe, Ken Hite, Pelgrane)

Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

White Wolf Wraith The Oblivion Guildbook Spooks and Oracles SC NM

By Martina McGrath, MD
June 5, 2018

20mm WW2 british - landing craft - ships (36153)25mm 7YW french - grenadiers 15 figures - inf (28757) Celtic Leather Belt Bag, Pouch Purse. Larp Cosplay RP Medieval Saxon Viking

Foam and Latex, Bendable Tonfa, Baton. Ideal for Costume or LARP

25mm ACW confederate - american civil war infantry 30 figures - inf (16080)

By Lea Borgi, MD
May 16, 2018

25mm ACW union - american civil war infantry 16 figures - inf (12431)25mm biblical assyrian - archers & slingers 18 figures - inf (32778)25mm classical greek - ancient cavalry 6 cavalry - cav (18590) Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”