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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

Tita's EPT Deeds of the Ever-Glorious SC VG

By Olivier Lucar
October 16, 2018

MARVEL SUPER HEROES THE LEFT HAND OF ETERNITY. New in shrinkwrap.West End Games (WEG) JLA Sourcebook DCU RPG 2000 DC Comics RARE Fantasy Flight Games Star Wars X-Wing Imperial Assault Carrier Miniature Expa...Star Wars Armada Maneuver ToolSTAR WARS LEGION COMPLETE STARTER CORE SET - NEW & SEALEDTriple Ace Fantasy RPG Land of Fire HC MINT

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By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

10mm Roman era roman - late auxiliaries 30 figs - inf (22414)1200th scale napoleonic ships French 64 gun line15mm Abrams tanks for team yankee15mm ACW mexican - regiment 32 figures - inf (27018) Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery”

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.White Wolf Vampire The Masquerade 5th The Camarilla (English) Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

15mm AWI united states - United States 30 Infantry - inf (SV924)15mm colonial mahdists - dervishes 24 figures - inf (35940)15mm fantasy lizards - spears 16 figures - inf (35324)15mm napoleonic austrian - regiment 24 figures - inf (29800) Call of Cthulhu RPG Delta Green Countdown 2nd printing 1999 Pagan Publishing

Hill Avalon Game Board english Resized AD 2210 Risk 3cf40azct91020-Toys & Games

Avalon Hill Board Game Risk 2210 AD Resized english

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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By Lea Borgi, MD
May 16, 2018

25mm ACW confederate - american civil war cavalry 10 cavalry - cav (12369)25mm ACW old west - indian 13 figures - inf (25395)25mm amazon infantry 18 figures (14258) Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”