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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.SUPERSLOT CHEVROLET CAMARO 1969 SUNOCO DONOHUE MINTER SCALEXTRIC UK S3650 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Item specifics

New: A brand-new, unused, unopened and undamaged item in original retail packaging (where packaging is ... Read moreabout the condition
Scale: 1:500
Brand: Herpa Vehicle Type: Boeing 787-8F
Material: Metal EAN: 4013150531023
Package: No MPN: 531023
Modified Article: Yes Series: UPS Airline N605UP
Special Features: boxed, Display Model
Herpa Wings 1 500 Boeing 747-8f Ups Airline N605up 531023 Modellairport500

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018


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By Lea Borgi, MD
May 16, 2018

Scalextric Legends Team Lotus Type 72 As Driven by Tony Trimmer C3657A New BoxedScalextric Porsche 911 GT3R Collector Centre Special 2001 C2388 gold 1 32 scaleSCALEXTRIC Slot Car C4103 McLaren F1 GTR LeMans 1995 Weathered Edition Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”